A tale of two biotech cities: Chicago and Baltimore

A tale of two biotech cities: Chicago and Baltimore

Chicago, Ill. – As my readers have seen from past columns, I like to juxtapose bioscience regions to better understand what’s happening in one part of the world that might be shared in another. Within the span of two days last week, I had the opportunity to sit through two regional bioscience events.
The first – a Maryland event held on Feb. 19 in Annapolis entitled “Maryland Bioscience in the 21st Century” – was put on by the Tech Council of Maryland, which includes the Maryland Biotech Association. The second – an Illinois event held in Chicago by iBIO – was entitled “Capitalizing on Progress.” Amazingly, the underlying themes of both were remarkably similar:
• A review of the major milestones achieved in the region to show development versus the prior year.
• Showcasing of some of the key biotech movers and shakers in the region.
• A yearning to be ranked in the top ranks of biotech clusters in the world with comparisons to the California clusters, Boston, and North Carolina.
While I can understand the first two regions, it’s surprising how North Carolina came up in both meetings. Maryland and Illinois are both part of larger bioscience clusters. Maryland participates in a region including Virginia and Washington, D.C., while Illinois is at the hub of the eight-state Midwest.
Comparison shopping
To be fair, the meetings were very different. While the Maryland meeting did represent an annual meeting, it was a half-day event. Maryland has opted to participate in a larger annual regional 1-1/2-day event called the Mid-Atlantic Biotech Conference, which usually draws more than 1,000 people.
On the other hand, iBIO has cut back its 1.3-day event to a one-day event focused on Illinois. Given that the BIO annual international conference is coming back to Illinois in 2010, Illinois would be well-served to try to do a regional type of event. Though this kind of event might be difficult to assemble with eight states, perhaps with neighbors Wisconsin, Indiana, Iowa, and Missouri it might be possible and important.
As each state has its own issues with biotechnology, I can understand the need to try and focus on a state approach (particularly key state incentives necessary to attract companies). The reality is this is an industry that has globalized. Competition doesn’t come from a neighboring state but from India, China, Australia, Israel, Brazil, Singapore, Korea, etc.
Both regions have hosted the annual BIO international conference in the past. BIO 2006 was held in Chicago as will BIO 2010. BIO 2005 was held in Washington, D.C., a stone’s throw from Baltimore. Let’s take look at how both of these states compare in terms of biotech characteristics:
Bioscience Comparison between Two States

Bioscience Characteristics Illinois Maryland
Population (millions) 12.8 5.6
# of Bioscience Companies ~ 100 >300
Big Pharma/Big Device Abbott, Baxter, Hospira Becton Dickinson
Foreign Life Science Companies Takeda, Astellas, TAP, Siemens, Toshiba Medical, Ajinomoto, Valent Biosciences Otsuka, Shin Nippon Biomedical Labs, AstraZeneca (MedImmune)
Number of International State Trade Offices 10 10
Federal Government Institutions Argonne National Labs, Fermi Labs, USDA FDA, NIH, National Cancer Institute, USDA, Institute of Genomic Research, National Science Foundation
Leading Research Universities University of Chicago, University of Illinois, Northwestern University (4 other med schools) Johns Hopkins, University of Maryland
Total Federal Research Funding *(millions) (2006 data) $1,158 $1,453
Federal Research Funding Rank in all states 8 6
State Biotech Legislative Caucus Yes Yes
State Angel Tax Credit Program No Yes
State SBIR Matching Funds Yes Yes
State Stem Cell Research Funding for Companies No Yes
Total Venture Capital Funding – 2007** (millions) $510.4 $635.3
Number of VC Deals – 2007 ** 70 99

*Source: www.researchamerica.org
**Source: www.pwcmoneytree.com; note: includes all sectors, not just biotechnology
Explaining the numbers
The above story obviously doesn’t give a complete picture. We would need to add a number of other categories. At first blush, Maryland has more government research spend and institutions than Illinois and many more bioscience companies. Maryland is probably more focused on drug development with a sprinkling of diagnostic and medical device companies.
On the other hand, Illinois has a much larger chunk of big life sciences companies.
Though it doesn’t have the university research concentration that Maryland has, Illinois does have a number of key universities with sizeable government research funding. Illinois has a large drug business and also an equally large medical device and diagnostics business along with agricultural biotech, clean tech, nanotech, and renewable fuels research.
The Illinois annual meeting did a very good job showing this diversity of biotech as well as highlighting the state’s excellent university research and key foreign life sciences companies. The Astellas U.S. president articulated clearly why Astellas was here and explained its growth plans.
On the other hand, Maryland’s life sciences meeting emphasized legislation.
A number of state representatives were there to talk about how they saw the importance of the local industry. Additionally, Maryland has just formed a Bioscience Advisory Committee to advise the governor on strategy and policy. This newly formed committee is composed of representatives from the leading university, FDA, NIH, leading biotech companies, the U.S. Army, and more.
Interestingly enough, the group is chaired by the CEO of Human Genome Sciences. Tom Watson is a longtime executive from Abbott Labs. Also of interest was that another up-and-coming biotech company CEO on a panel came out of Eli Lilly, which means that once again the Midwest is a good source for managerial talent.
Dialing it down
So what does this all mean? A really great meeting might have included key aspects from both state’s biotech agenda. Both states would be well-served to sit down with each other and share notes because both have some great programs going on and could learn from each other.
Meanwhile, Boston and San Francisco are hardly standing still and have already initiated state efforts to maintain their world leadership in this vital industry. This means that both Maryland and Illinois need to dial up the state government involvement in their own industries. It was an interesting couple days. See you soon!
Previous articles by Michael Rosen
Get set because here come two Olympics, athletics and biotech
Michael Rosen: 2007: M&As and IPOs continue in the Midwest life science sector
Michael Rosen: U.S. can learn from growth of biofuels in Latin America
Michael Rosen: 2007: The best and worst of times for Big Pharma
Michael Rosen: Combination therapy: Back to future or wave of future?
Michael Rosen: Angel investing slows during first half of 2007

Michael S. Rosen is president of Rosen Bioscience Management, a company that provides CEO services, including financing and business and corporate development to start-up and early-stage life science companies such as Renovar and Immune Cell Therapy. Rosen also is a founder and board member of the Illinois Biotechnology Industry Organization. He can be reached at rosenmichaels@aol.com.
This article previously appeared in MidwestBusiness.com, and was reprinted with its permission. The article is not meant to be a stock recommendation.
The opinions expressed herein or statements made in the above column are solely those of the author, and do not necessarily reflect the views of Wisconsin Technology Network, LLC.
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